Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration
نویسندگان
چکیده
منابع مشابه
Citrate Pharmacokinetics in Critically Ill Patients with Acute Kidney Injury
INTRODUCTION Regional citrate anticoagulation (RCA) is gaining popularity in continous renal replacement therapy (CRRT) for critically ill patients. The risk of citrate toxicity is a primary concern during the prolonged process. The aim of this study was to assess the pharmacokinetics of citrate in critically ill patients with AKI, and used the kinetic parameters to predict the risk of citrate ...
متن کاملSustained Low-Efficiency Daily Diafiltration for Diabetic Nephropathy Patients with Acute Kidney Injury
OBJECTIVE To investigate the efficacy, safety and cost of treating patients with acute kidney injury (AKI) and diabetic nephropathy (DN) with continuous renal replacement therapy (CRRT) or sustained low-efficiency daily diafiltration with hemofiltration (SLEDD-f). SUBJECTS AND METHODS Medical records of patients with AKI/DN from January 2006 to December 2012 were reviewed. Fifty-five patients...
متن کاملUsing population pharmacokinetics to dose gentamicin 1 during extended - daily diafiltration in critically ill patients with 2 acute kidney injury
28 The objective of this prospective pharmacokinetic study was to describe the variability of 29 gentamicin plasma concentrations in critically ill patients with AKI necessitating extended30 daily-diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently 31 perform Monte Carlo dosing simulations to determine which dose regimen achieves 32 pharmacodynamic targets most co...
متن کاملUsing population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury.
The objective of the present prospective pharmacokinetic study was to describe the variability of plasma gentamicin concentrations in critically ill patients with acute kidney injury (AKI) necessitating extended daily diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently perform Monte Carlo dosing simulations to determine which dose regimen achieves the pharmacodyna...
متن کاملPharmacokinetic Behavior of Theophylline following PEEP in Critically Ill Patients with Acute Lung Injury
The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2018
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dky057